While CBD does not directly activate our CB1 and CB2 receptors, it works with them indirectly to create those great benefits we have come to know and love. Another complicated aspect is that CBD does not directly bind to CB1 or CB2 receptors. Instead, CBD indirectly impacts these receptors by activating TRPV1 receptors that control pain perception, body temperature, and inflammation. The impact of CBD on the receptors in the endocannabinoid system is actually quite complicated.
When we are ill or in pain, the amount of CB1 receptors in our body increases which aids in the management and reduction of inflammation, pain and nausea. So, according to research carried out on both animals and cancer sufferers, they help to make us feel not quite as bad as we otherwise would. Endocannabinoids bind to the endocannabinoid receptors throughout our body and, when needed, prompt the ECS CBD oil into action.
Cbd Oil And The Endocannabinoid System 101
Yet hemp and the influence it could have on the endocannabinoid system is driving growth, experimentation and innovation even as the Food and Drug Administration has not confirmed a regulatory pathway for these products. Certain activities not only enhance the endocannabinoid system, but also allow you to feel great, improve your health and effectiveness of cannabis. Phthalates are added to plastic, tin containers and water bottles and they are known to block cannabinoid receptors and negatively impact our hormonal system. Use glass or stainless steel food containers and packaging and never eat food that’s been heated in plastic. Cocao powder has three compounds that have very similar chemical structures to endocannabinoids.
- THC binds to both CB1 and CB2 receptors and its effects on both the mind and body can be powerful and at times unwanted.
- The ECS has two main cannabinoid receptors, which are known as CB1 and CB2.
- The CB2 receptors are found throughout the immune system, including the gastrointestinal tract and in low densities in the central nervous system.
- CB1 receptors primarily located in the central nervous system and the brain work to help regulate pain, sleep, mood, cognitive function and appetite, among other functions.
- These receptors are associated with immune function, gastrointestinal function, inflammation and pain responses.
How Does Cbd Actually Effect Your Body?
And we are here to explain exactly how it works, and exactly why CBD makes you feel so good. CB1 is mostly found inside the brain, while CB2 is spread throughout most of the immune system. Contrary to popular belief, CBD does not tend to activate either of these receptors. It’s been less than 18 months since the 2018 Farm Bill removed hemp from the Controlled Substances Act and legally differentiated hemp from marijuana as containing less than 0.3% THC.
These three compounds can slow down the metabolism of your cannabinoids, resulting in higher levels of endocannabinoids and also have some activity similar to cannabinoids. An added bonus is it may help prevent dementia, heart disease and strokes. Many foods and activities can have a profound effect on the endocannabinoid system and as a result allow it to function optionally.
CBD is not just any natural alternative method; it is the one that your body is already built for. Some scientists think that it actually binds to a yet to be discovered receptor, although more research is needed if we are to discover exactly how this cannabinoid works in so many amazing ways. Whereas THC binds with the brain’s CB1 receptors to produce a “high”, CBD doesn’t appear to function in this way and can even help to prevent THC bonding to them, lessening its psychotropic effects.
Without optimizing the internal cannabinoid system, we risk losing the ability to maximize how cannabis can help us. Remember the endocannabinoid system has to be fully optimal and without that, you won’t be able “to make chicken salad from chicken poop”. This is when your body is just not producing enough endocannabinoids on its own. This is the reason that so many have found relief using CBD products because it’s helping our ECS do the job it is designed to do. If our Endocannabinoid System is struggling to keep up, CBD is there to help it do its thing.